Insights into the world of aesthetic beauty
Skin Boosting and renewal

Everything you need to know about Bio-stimulators

Part II in our NEW PROTOCOL Series

Why we are so excited about injectable Bio-stimulators!

Preventing, Maintaining and Restoring skin health has always been the ultimate goal for Dr Norup.  Bio-stimulation targets the skin itself and it upgrades the skin with health and strength causing minimal downtime, without adding volume.  Skin factory cells need potent, long lasting stimulation in order to produce the goods.

Injectable Bio-stimulators do exactly that, as they are injected into or beneath the skin and remain active there for up to 4 weeks.

Bio-stimulation peels are potent for up to 2 weeks.

Mesotherapy cocktails remain active for up to 48 hours, and are less potent but also contain other ingredients that target skin problems.

Skincare, rely on penetration through the skin barrier and remain for hours rather than days, yet they if applied daily, they can make a big difference.

Now Let’s explore our options!


A very popular option, known as a strong hydrating injectable treatment for face and body, which promotes collagen and elastin stimulation.

Profhilo Face
Profhilo face is suitable for face, neck and décolletage.

Profhilo Body
Profhilo Body is suitable for the abdomen, thighs, arms, knees, and hands.

After injection, Profhilo remains in the skin for 4 weeks and stimulates natural healing processes. The treatment works in two phases, hydrating your skin first, then stimulating the production of essential new collagen and elastin during the following 3 months.

Profhilo’s main effect is to visibly restore firmness and elasticity in the skin. It also works very well for conditions such as rosacea, sensitivity, and thin/dry skin with fine, crepey lines.

Prohilo skin repair


Nucleofill is derived from wild salmon stem cells and contains a pure Polynucleotide gel (DNA and RNA biopolymers).

Depending on the injection technique, it stimulates all of the biological tissues for 2-3 weeks:
Fibroblasts (skin factory cells): Generating high-quality collagen, elastin & hydration.
Osteoblasts (bone factory cells): Maintaining/increasing bone density.
Myofibroblasts (smooth muscle factory cells in the skin): Creating “the gym effect” by directly tightening the myo-fibrills and lifting the skin.
Adipose (fat cells): Maintaining healthy & firm fat components, including the stem cells within.

Nucleofill stimulates collagen, elastin and long-term hydration. It stimulates the tiny muscles superficially in the skin and allows for a strong anti-oxidant action by providing the skin with a cleansing effect and increasing circulation. Nucleofill mainly targets skin laxity but also helps with hydration, firming, contouring and definition.

Nucleofill 3 formulations
Soft – Eye and lip area
Medium – Face, neck and body
Strong – Face, neck and body

Nucleofil wrinkle reduction


Jalupro is a very potent multi-functional bio-stimulator that offers the power of amino acids, peptides & high concentrations of pure HA, which provide skin cells with the components it needs for function and development.

This injectable product delivers a boost of hydration and nutrition, stimulating collagen and elastin within the skin. It can tighten and lift the skin depending on the selected treatment and formulation as it allows the targeting of facial ligaments. Each formulation has a specific application and outcome. They can be intermixed to suit a combined protocol and remain in the skin for 2 – 3 weeks.

Jalupro 3 formulations:

Jalupro Classic
This product gives a super fast boost to the skin, containing a low molecular weight HA (hyaluronic acid) and amino acids.

This deep penetration in the epidermis stimulates fibroblast proliferation, collagen synthesis and elastin production. This significantly improves skin tone, brightening, hydration and skin quality. This formulation can be mixed with other injectables, such as Botox, for added benefits.

Jalupro Classic is commonly used on the face for younger skin or immediate hydration and due to the low viscosity it can safely be injected around the eyes, upper lip and forehead but it is also used on the neck, décolleté, arms, knees and hands.

Formulation: 3 ml containing 30 mg of low molecular weight HA and 100 mg of 4 essential Amino Acids.

This product gives a more targeted treatment, which can be used for the treatment of deeper lines and wrinkles due to heavier molecular weight. It is suitable for face, lip, neck, décolletage and hands for more aged skin.

Formulation: Total of 2.5 ml containing 20 mg of high molecular weight HA and 80 mg of 4 essential Amino Acids.

Jalupro Super Hydro
Suitable for the face and neck. super Hydro has a superior mix of amino acids, including both high and low weight HA as well as peptides. This means that the stimulation comes from 4 different sources and the AA cluster penetrates deep into the skin, providing strong lifting effects, firmness, and deep hydration.

Formulation: Premixed 2.5ml syringe containing 80 mg of high and low molecular weigh HA, 3 Biomimetic Peptides for cell activation, and 7 essential Amino Acids.

Jalupro skin treatment


Sunekos is an injectable bio-stimulator very similar to Jalupro in that it contains Hyaluronic acid and amino acids, thereby stimulating both collagen and elastin plus it also hydrates.

Sunekos Performer formulation:
Can be injected for immediate hydration and in high-risk areas such as the forehead, upper lip and around the eyes due to the low molecular weight.
Premixed 3.5 ml vial containing a total of 128 mg of 6 amino acids and 35 mg of low molecular weight HA (50-250KDa).

Sunekos 1200 formulation:
3 ml mix of high molecular weight (1200 KDa) and 6 essential amino acids.

Body formulations:
Effective for stretch marks, body scars and sagging skin on arms, belly, hands and other areas of the body.
10 ml mix of low molecular weight (50-250 KDa) HA, plus 6 AA.

Targeted for cellulite on the thighs, legs, belly, etc.
10 ml mix of low molecular weight (200 KDa) HA, 6 AA and carbonate+bicarbonate salts that neutralise the acidosis in cellulite tissue. T

Sunekos Biostimulator


To find out which treatment is suitable for your skin, book a skin consultation at the Norup Clinic